Peyronie's disease is an acquired condition that affects 9% of men. One in 11 will present with Peyronie’s disease in their lifetime. Peyronie’s disease is a scarring process in the penis that leads to a plaque buildup and development of a curvature and narrowing or indentations of the penis. Patients may have painful erections as the curvature evolves or it may resolve by itself.

Patients often ask whether pills, such as Vitamin E, have any benefit in the management of Peyronie’s disease. And the short answer is: no. Pills such as Vitamin E, Pentoxifylline, Viagra, Cialis and all other forms of pills have not consistently shown any benefit in improving the conditions related to Peyronie's disease, i.e., the curvature, the deformity, or the pain related to the condition.

As such, all international societies such as the American Urologic Association, the International Society for Sexual Medicine, and the Sexual Medicine Society of North America all recommend against using Vitamin E for the management of Peyronie's disease. There is currently no evidence to support the use of Vitamin E or any other oral pills or supplements for the management of Peyronie’s disease. As such, it is not recommended.



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